Dr. Chan Ching Wan
Konsultan & Ahli Bedah Payudara Senior
MBChB (Edin), FRCS (Edin), FRCS (Glas), PhD (Bristol)
MBChB (Edin), FRCS (Edin), FRCS (Glas), PhD (Bristol)
Sebagai konsultan senior kami, Dr. Chan Ching Wan memiliki perhatian khusus di dalam pembentukan sel kanker dan bagaimana cara kanker dapat dihambat dan diobati. Dr. Chan juga merupakan Asisten Profesor di Yong Loo Lin School of Medicine, NUS, sejak tahun 2009. Sebelum bergabung dengan Solis, beliau adalah Kepala Klaster Subspesialisasi untuk Layanan Payudara di Singapore’s National University Health System. Dr Chan juga pernah menjabat sebagai Kepala Program Onkologi Tumor Payudara di National Cancer Institute Singapura.
Pelatihan dan Kualifikasi
Dr. Chan memperoleh gelar dokternya dari University of Edinburgh Medical School. Selanjutnya, Dr. Chan menyelesaikan pelatihan spesialis tingkat dasar dan tingkat lanjut dalam bedah umum di Singapore General Hospital dan lulus dari program tersebut pada tahun 2007. Beliau telah menjadi fellow of Royal College of Surgeons of Edinburgh dan fellow of Royal College of Physicians and Surgeons of Glasgow sejak tahun 1999. Di saat pendidikan bedahnya, Dr. Chan menerima Beasiswa NMRC Totalisator Board di mana dia menyelesaikan gelar PhD di bidang Neuroendocrinology di Universitas Bristol pada tahun 2004.
Dianugerahi Penghargaan HMDP Award and Skills Attachment Award
Dr. Chan menerima penghargaan Health Manpower Development Program (HMDP) Award sebagai dokter Onkoplastik Payudara di Nottingham Breast Institute, UK pada tahun 2008. Beliau terlatih dalam prosedur mammoplasti terapeutik, flap latissimus dorsi untuk rekonstruksi payudara parsial dan total, rekonstruksi implan, operasi simetris kontralateral, dan pemindahan lemak untuk defisit volume dan remodelling kontur. Selain itu, Dr. Chan membantu mengembangkan studi transisi yang ditujukan untuk berbagai aspek diagnosis, deteksi dan pengobatan kanker.
Saat dia menempuh pendidikannya, dia juga menerima Penghargaan Skills Attachment Award digital mamografi dengan peningkatan kontras (team AMDA Award) pada tahun 2018
Artikel Oleh Dr. Chan Ching Wan
Publikasi Medis oleh Dr. Chan Ching Wan
Optoacoustic characterization of breast conserving surgery specimens – A pilot study. PHOTOACOUSTICS, 19, 9 pages (2020)
G. Balasundaram, Goh, Y., Moothanchery. M, Attia, A., Lim, H.Q., Burton, N. C., Olivo, M., Chan, C.W.
Maintaining breast cancer care in the face of COVID-19. British Journal of Surgery, 107(10), 1245-1249 (2020)
Ng, C. W. Q., Tseng, M., Lim, J. S. J., & Chan, C. W.
European polygenic risk score for prediction of breast cancer shows similar performance in Asian women. NATURE COMMUNICATIONS, 11(1), 11 pages (2020)
Ho, W. K., Tan, M. M., Mavaddat, N., Tai, M. C., Mariapun, S., Li, J., Antoniou, A. C., Chan, C. W.
Ultrasound Guided Optoacoustic Tomography in Assessment of Tumor Margins for Lumpectomies. TRANSLATIONAL ONCOLOGY, 13(2), 254-261 (2020)
Goh, Y., Balasundaram, G., Moothanchery, M., Attia, A., Li, X., Lim, H. Q., Olivo, M., Chan, C. W.
Barcoded DNA nanostructures for the multiplexed profiling of subcellular protein distribution.. Nat Biomed Eng, 3(9), 684-694 (2019)
Sundah, N. R., Ho, N. R. Y., Lim, G. S., Natalia, A., Ding, X., Liu, Y., Shao, H., Chan, C. W.
The functional ALDH2 polymorphism is associated with breast cancer risk: A pooled analysis from the Breast Cancer Association Consortium. Molecular Genetics and Genomic Medicine, 7(6) (2019)
Ugai, T., Milne, R. L., Ito, H., Aronson, K. J., Bolla, M. K., Chan, T., Matsuo, K., Chan, C. W.
Investing in gender equity in health and biomedical research: a Singapore perspective. LANCET, 393(10171), E21-E22 (2019)
Yoong, J., Alonso, S., Chan, C. W., Clement, M. V., Lim, L. H. K., & Archuleta, S.
Multispectral Optoacoustic Tomography in Assessment of Breast Tumor Margins During Breast-Conserving Surgery: A First-in-human Case Study. CLINICAL BREAST CANCER, 18(6), E1247-E1250 (2018)
Goh, Y., Balasundaram, G., Moothanchery, M., Attia, A., Li, X., Lim, H. Q., Olivo, M., Chan, C. W.
A genome-wide association study identifies three novel genetic markers for response to tamoxifen: A prospective multicenter study. PLOS ONE, 13(8), 14 pages (2018)
Onishi, H., Udagawa, C., Kubo, M., Nakamura, S., Akashi-Tanaka, S., Kuwayama, T., Zembutsu, H., Chan, C. W.
Ductal carcinoma in-situ arising within benign phyllodes tumours. ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 100(4), E97-E102 (2018)
Lui, S. A., Oh, H. B., Wang, S., & Chan, C. W.
Triple negative breast cancer in Asia: An insider’s view. CANCER TREATMENT REVIEWS, 62, 29-38 (2018)
Wang, C., Kar, S., Lai, X., Cai, W., Arfuso, F., Sethi, G., Kumar, A. P., Chan, C. W.
Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study. CLINICAL CANCER RESEARCH, 23(8), 2019-2026 (2017)
Zembutsu, H., Nakamura, S., Akashi-Tanaka, S., Kuwayama, T., Watanabe, C., Takamaru, T., Nakamura, Y. , Chan, C. W.
Genomic predictors of neoadjuvant chemotherapy (NACT) response in breast cancer (BC).. In JOURNAL OF CLINICAL ONCOLOGY Vol. 35 (pp. 5 pages). Chicago, IL: AMER SOC CLINICAL ONCOLOGY (2017)
Wong, A. L. A., Tan, K. T., Sundar, R., Ow, S., Pang, A., Yap, H. -L., Lee, S. C., Chan, C. W.
Phase Ib/II randomized, open-label study of doxorubicin and cyclophosphamide with or without low-dose, short-course sunitinib in the pre-operative treatment of breast cancer. ONCOTARGET, 7(39), 64089-64099 (2016)
Wong, A. L. A., Sundar, R., Wang, T. -T., Ng, T. C., Zhang, B., Tan, S. H., Lee, S. C., Chan, C. W.
High expression of intratumoral stromal proteins is associated with chemotherapy resistance in breast cancer. ONCOTARGET, 7(34), 55155-55168 (2016)
Wang, T., Srivastava, S., Hartman, M., Buhari, S. A., Chan, C. W., Iau, P., Lee, S. C.
Simvastatin-induced breast cancer cell death and deactivation of PI3K/Akt and MAPK/ERK signalling are reversed by metabolic products of the mevalonate pathway. ONCOTARGET, 7(3), 2532-2544 (2016)
Wang, T., Seah, S., Loh, X., Chan, C. W., Hartman, M., Goh, B. C., & Lee, S. C.
Accelerated partial breast irradiation in an Asian population: dosimetric findings and preliminary results of a multicatheter interstitial program. ONCOTARGETS AND THERAPY, 9, 5561-5566 (2016)
Koh, Y. V., Tan, P. W., Buhari, S. A., Iau, P., Chan, C. W., Shen, L., Tang, J. I. H., Chan, C. W.
Genomic landscapes of breast fibroepithelial tumors. NATURE GENETICS, 47(11), 1341-+ (2015)
Tan, J., Ong, C. K., Lim, W. K., Ng, C. C. Y., Thike, A. A., Ng, L. M., Teh, B. T., Chan, C. W.
Cell viability and angiogenic potential of a bioartificial adipose substitute. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 9(6), 702-713 (2015)
Panneerselvan, A., Nguyen, L. T. H., Su, Y., Teo, W. E., Liao, S., Ramakrishna, S., & Chan, C. W.
Differential cell adhesion of breast cancer stem cells on biomaterial substrate with nanotopographical cues.. J Funct Biomater, 6(2), 241-258 (2015)
Tan, K. K. B., Giam, C. S. Y., Leow, M. Y., Chan, C. W., & Yim, E. K. F., Chan, C. W.
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. NATURE GENETICS, 47(4), 373-U127 (2015)
Michailidou, K., Beesley, J., Lindstrom, S., Canisius, S., Dennis, J., Lush, M. J., Easton, D. F., Chan, C. W.
Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium. HUMAN MOLECULAR GENETICS, 23(22), 6096-6111 (2014)
Milne, R. L., Burwinkel, B., Michailidou, K., Arias-Perez, J. I., Pilar Zamora, M., Menendez-Rodriguez, P., .Easton, D. F., Chan, C. W.
Simvastatin induced apoptosis and suppressed proliferation of breast cancer through deactivating PI3K/Akt/mTOR pathway. In CANCER RESEARCH Vol. 74 (pp. 2 pages). San Diego, CA: AMER ASSOC CANCER RESEARCH (2014)
Wang, T., Seah, S., Chan, C. W., Hartman, M., Dar, N. N. T., Iau, P., Lee, S. C.
Phase II study of neoadjuvant weekly paclitaxel and carboplatin with lapatinib in HER2+breast cancer.. In JOURNAL OF CLINICAL ONCOLOGY Vol. 32 (pp. 1 page). Chicago, IL: AMER SOC CLINICAL ONCOLOGY (2014)
Wong, A. L. A., Tan, S. H., Soh, I. P. T., Tan, C. S., Lim, Y. W., Pang, A., Lee, S. C., Chan, C. W.
Effect of low-dose, short-course sunitinib (Su) on tumor vasculature and tumor blood flow for enhancement of chemotherapy efficacy in breast cancer.. In JOURNAL OF CLINICAL ONCOLOGY Vol. 32 (pp. 1 page). Chicago, IL: AMER SOC CLINICAL ONCOLOGY (2014)
Wong, A. L. A., Sundar, R., Ow, S. G. W., Wang, T. T., Ng, T. -C., Chan, C. W., Lee, S. C.
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. NATURE GENETICS, 45(4), 392-398 (2013)
Garcia-Closas, M., Couch, F. J., Lindstrom, S., Michailidouo, K., Schmidt, M. K., Brook, M. N., Kraft, P., Chan, C. W.
Low-dose, short-course sunitinib may normalize tumor vasculature and improve tumor blood flow to enhance chemotherapy efficacy in breast cancers. In JOURNAL OF CLINICAL ONCOLOGY Vol. 30 (pp. 1 page). Chicago, IL: AMER SOC CLINICAL ONCOLOGY (2012)
Lee, S. -C., Wong, A. L. A., Ng, T. C., Thng, C. H., Wang, T. T., Tiemsim, M. C., Goh, B. C., Chan, C. W.
Extracellular matrix protein expression is associated with chemotherapy resistance in breast cancer. In CANCER RESEARCH Vol. 72 (pp. 1 page). AMER ASSOC CANCER RESEARCH (2012)
Wang, T., Guo, T., Sze, S. K., Hartman, M., Buhari, S. A., Chan, C. W., Lee, S. C.
Serial changes in the expression of breast cancer-related proteins in response to neoadjuvant chemotherapy. ANNALS OF ONCOLOGY, 22(8), 1748-1754 (2011)
Chuah, B. Y. S., Putti, T., Salto-Tellez, M., Charlton, A., Iau, P., Buhari, S. A., Lee, S. C., Chan, C. W.
A Commentary on Delayed Presentation of Breast Cancer in Singapore. ASIAN PACIFIC JOURNAL OF CANCER PREVENTION, 12(6), 1635-1639 (2011)
Chang, G., Chan, C. W., & Hartman, M.
Pharmacokinetics and pharmacodynamics of docetaxel with or without ketoconazole modulation in chemonaive breast cancer patients. ANNALS OF ONCOLOGY, 21(11), 2175-2182 (2010)
Lim, Y. -W., Goh, B. C., Wang, L. Z., Tan, S. H., Chuah, B. Y. S., Lim, S. E., Lee, S. C., Chan, C. W.
Autologous fat transfer – a review of the literature with a focus on breast cancer surgery. Journal of Plastic, Reconstructive and Aesthetic Surgery, 61(12), 1438-1448 (2008)
Chan, C. W., McCulley, S. J., & Macmillan, R. D.
Volume displacement techniques and therapeutic mammoplasty: The Nottingham experience. Advances in Breast Cancer, 5(1), 10-12 (2008)
Macmillan, R. D., Chan, C. W., & McCulley, S. J.
A novel member of the SAF (scaffold attachment factor)-box protein family inhibits gene expression and induces apoptosis. Biochemical Journal, 407(3), 355-362 (2007)
Chan, C. W., Lee, Y. B., Uney, J., Flynn, A., Tobias, J. H., & Norman, M.
